Medication
14th August 2025

5 reasons Wegovy works

Here are five science-backed reasons why Wegovy remains a powerful weight loss treatment in 2025.

Article by CheqUp
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With so much talk about new weight loss medications and changing prices, it’s easy to feel unsure about what really works. But here’s the truth: Wegovy is still one of the most effective, trusted tools available for people who want to lose weight and keep it off.

In a world full of noise, hype and breaking headlines, this is your reminder that real progress is still possible with a treatment that’s been trusted, studied, and proven time and again.

Here are five reasons why Wegovy (also known as Ozempic)  remains one of the most effective and accessible options for people looking to lose weight and improve their health

1. Wegovy delivers real, sustainable weight loss

Wegovy (AKA Ozempic) has helped thousands of people achieve meaningful weight loss – and keep it off. In large clinical trials, patients lost on average around 15% of their body weight over 68 weeks.*

That kind of result isn’t just clinically significant – it’s life-changing. For many people, Wegovy supports progress that’s hard to achieve with diet and exercise alone.

Yes, Mounjaro has shown higher average weight loss in trials, but for most people, Wegovy still provides more than enough support to reach their goals.

2. It’s trusted, available and approved in the UK

Wegovy has been available in the UK since 2023 and is approved by NICE for people living with obesity or weight-related health conditions. It’s prescribed by NHS services and private clinics, with a stable supply chain and consistent pricing. (Wegovy sells under the brand name ‘Ozempic’ in the US)

As of now, Mounjaro has more limited availability – and with recent announcements suggesting potential price increases, some people may find it harder to access or afford. Wegovy offers the reassurance of availability, regulatory approval, and wide-scale use across the UK.

3. Most people don’t need ‘more’ – Wegovy is enough

It’s easy to compare numbers and wonder if more weight loss is always better. But for most people, Wegovy delivers more than enough.

Losing 15% of your body weight can:

  • Improve blood sugar control
  • Lower the risk of heart disease
  • Reduce joint pain and sleep issues
  • Boost mood, energy and confidence

When Wegovy works, it works well – and for many, it strikes the right balance between effectiveness, tolerability and support.

4. It’s well understood – with fewer surprises

Wegovy is a GLP-1 receptor agonist. Mounjaro is a dual-agonist (GLP-1 and GIP), which may lead to slightly greater weight loss but can also come with more intense side effects for some people.

Wegovy has a simpler, more established mechanism. It’s been studied extensively and is supported by years of clinical use – which means your prescriber understands how to get the best from it, and how to support you through the journey.

For people switching from Mounjaro, or starting treatment for the first time, Wegovy offers a clear, steady path with fewer unknowns. It’s also gained huge traction in America under the name Ozempic.

5. Wegovy is more affordable – especially if Mounjaro prices rise

If you’re funding your own treatment, cost matters. With Mounjaro expected to rise in price following recent political and economic shifts, Wegovy may soon become the more affordable and accessible option.

It’s already the more widely available medication in the UK, and is often included in supported programmes with coaching, advice and structured plans.

When you combine clinical effectiveness with lower cost and more consistent access, Wegovy becomes a very strong choice.

Still unsure? Let’s talk about it

It’s natural to have questions when headlines change. But the fundamentals haven’t: Wegovy remains a powerful, proven tool for weight loss – and one that’s helping people every day.

If you’re thinking of switching from Mounjaro, we’re here to help.

You can speak to our team, ask questions, or explore a treatment plan that fits your goals, your health, and your budget.

*Wilding, et al. “Once-Weekly Semaglutide in Adults with Overweight or Obesity.” New England Journal of Medicine, vol. 384, no. 11, 2021

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The prescribing of medicines through our website is carried out by CheqUp Health Limited (registered with Care Quality Commission with number 1-17083303713). Our medications are dispensed by Chequp Health Limited.Chequp Health Limited is regulated by the General Pharmaceutical Council (number 9012707) where the Superintendent Pharmacist is Aaron Arman (GPhC number 2216043). You can view our full pharmacy terms and regulatory information, including details on how to contact us or the relevant regulatory bodies, by clicking here.

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